Using Depakote during pregnancy may increase the risk of serious birth defects that can develop early in pregnancy, even before you know you are pregnant. Your family or other caregivers should also be alert to changes in your mood or symptoms. ![]() Your doctor will need to check your progress at regular visits. ![]() Some people have thoughts about suicide while taking Depakote. Liver problems caused by a genetic mitochondrial disorder ĭepression, mental illness, or suicidal thoughts or actions orĪ family history of a urea cycle disorder or infant deaths with unknown cause. To make sure this medicine is safe for you, tell your doctor if you have: You should not use Depakote if you are allergic to divalproex sodium, or if you have:Ī genetic mitochondrial (MYE-toe-KON-dree-al) disorder such as Alpers' disease or Alpers-Huttenlocher syndrome, especially in a child younger than 2 years old.ĭivalproex sodium can cause liver failure that may be fatal, especially in children under age 2 and in people with liver problems caused by a genetic mitochondrial disorder. Stopping suddenly may cause a serious, life-threatening type of seizure. Do not use Depakote to prevent migraine headaches if you are pregnant.Ĭall your doctor at once if the person taking this medicine has signs of liver or pancreas problems, such as: loss of appetite, upper stomach pain (that may spread to your back), ongoing nausea or vomiting, dark urine, swelling in the face, or jaundice (yellowing of the skin or eyes).ĭo not stop using this medicine without your doctor's advice. Divalproex sodium may harm an unborn baby, but having a seizure during pregnancy could harm both mother and baby. You should not use divalproex if you have liver disease, a urea cycle disorder, low platelet counts, or a genetic disorder such as Alpers' disease or Alpers-Huttenlocher syndrome.ĭo not start or stop taking Depakote during pregnancy without your doctor's advice. Warningsĭepakote can cause liver failure that may be fatal, especially in children under age 2 and in people with liver problems caused by certain genetic disorders. The tablets are sometimes used together with other seizure medications.ĭepakote tablets are also used in adults to prevent migraine headaches, or to treat manic episodes related to bipolar disorder (manic depression). This medicine is sometimes used together with other seizure medications.ĭepakote tablets and capsules are used to treat seizures in people with epilepsy who are at least 10 years old. Depakote is used to treat various types of seizure disorders. Last updated on Apr 11, 2022.ĭepakote affects chemicals in the body that may be involved in causing seizures. Medically reviewed by Sophia Entringer, PharmD. ![]() Generic name: divalproex sodium ĭrug class: Fatty acid derivative anticonvulsants
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